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Pipeline
We take aim at the world’s most intractable diseases. Our portfolio spans both novel and known (but traditionally undruggable) targets.
Indication
rModality
Target
Discovery
Pre-clinical
Clinical
IL-2
Cancer
Metabolic
Immunity
Cancer
Auto-immune
Alzeimer's disease
MYC
Inframmation
Auto-immune
SM
Inframmation
Auto-immune
SM
SM
SM
SM
IL-1β
IL-1
β
SM
IL-1α
PTPN2
Cancer
Auto-immune
Inframmation
Auto-immune
ALS
Alzeimer's disease
ALS
1
Alzeimer's disease
IL-1RA
SM
ASO
FLCN
FLCN
Unless otherwise indicated, the rModality is a small molecule
rModality = RNA-targeted modality